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Interesting that Lexapro was approved for adolescents given that Celexa wasn't approved for pediatric use. Lexapro blocks the re-absorption of serotonin by the first nerve cell. You should never take more than one dose of Lexapro at any time. Evidence suggests an imbalance of serotonin, Escitalopram improves symptoms of depression. Escitalopram helps to restore the brain's chemical balance by increasing the available supply of serotonin, a natural substance in the brain believed to influence mood.