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Steroid drug is used to reduce inflammation and alleviate symptoms in a variety of disorders, including rheumatoid arthritis and severe cases of asthma. Steroid drug is used to reduce inflammation and alleviate symptoms in a variety of disorders, including rheumatoid arthritis and severe cases of asthma. Deltasone is used in the management of adrenal insufficiency unless a more potent mineral corticoid is administered concomitantly. You are allergic to Prednisolone, or if you have any of these conditions, you may need a dose adjustment or special tests to safely take Prednisolone. Since prednisone is used for treating several types of arthritis systemic lupus, allergic reactions, asthma and severe psoriasis.