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Do not take Diflucan without first talking to your doctor if you have liver disease, kidney disease, or a heart rhythm disorder. Fluconazole is a very widely used antifungal agent. Diflucan is an antifungal medication, used to treat infections caused by the fungus Candida. Fluconazole is used to treat vaginal yeast infections. Fluconazole disturbs the production of ergosterol that is essential component of the fungi cell, resulting in changing permeability. Read all of the Diflucan prescription yeast infection treatment medication before placing your order from the online pharmacy. You experience any of the serious side effects, stop taking Diflucan right away.